A root-cause programme for sustainable weight loss — built on functional diagnostics, hormonal balance, personalised nutrition, and lifestyle design.
The rise of obesity has placed the health of an entire generation at risk.
— Tom Vilsack, Former U.S. Secretary of Agriculture
Many direct and indirect factors drive weight gain. Diet is the most visible — but rarely the only one.
The first eight triggers below are dietary. Below the list, we explore the deeper biological and lifestyle drivers most weight-loss programmes ignore.
8 dietary triggers
Most people accumulate several daily
Five biological and lifestyle factors that quietly sabotage even the most disciplined eaters.
Reduces Leptin (the appetite-suppressing hormone) and increases Ghrelin (the hunger hormone) — stimulating appetite and fat storage. Most patients with stubborn weight have sleep debt.
A predominantly sedentary lifestyle — long sitting hours, low activity, no structured exercise — puts the body at a high risk of weight gain and metabolic dysfunction.
Per the Journal of Clinical Endocrinology and Metabolism: atypical antipsychotics, anticonvulsants & mood stabilisers, hypoglycaemic medications, antidepressants, and glucocorticoids are all directly linked to weight gain.
Chemicals that interfere with hormone levels — especially liquid fructose in corn syrup — are linked to fatty liver and Cardiometabolic Syndrome (per the World Journal of Gastroenterology). Avoid them entirely.
A faulty fat-mass and obesity-associated gene (FTO) and elevated Ghrelin levels can drive appetite and fat storage. Genetic testing tells us what you're working with.
Beyond the visible — obesity sends signals through every body system.
Every programme is built around your bloodwork, hormonal panel, gut health, and (where useful) genetic profile — not a generic calorie target.
Dr. Sachdeva and our clinical team coordinate testing, nutrition, hormone work, lifestyle coaching, and movement under one roof — with weekly check-ins and progressive plan adjustments.
Get a personalised health assessment calibrated for Indian body types — with treatment recommendations from Dr. Sanjay Sachdeva's root-cause approach
Enter your details to see your personalised health assessment and treatment recommendations.
Using WHO Asian BMI thresholds — calibrated for Indian body types. Standard thresholds may underestimate health risk for South Asians.
BMI is a screening tool, not a diagnosis. Your Metabalance consultation includes a comprehensive functional assessment that goes beyond BMI to identify the root cause of any weight-related health concerns.
A four-pillar programme to reduce symptoms, address root causes, and restore optimal health — individualised for every patient.
Hormonal imbalances drive weight gain in ways diet cannot fix. BHRT uses bio-identical hormones to restore optimal levels of estrogen, progesterone, testosterone, thyroid, and cortisol — matched to your lab results.
Built on your genetic profile, food sensitivities, and metabolic markers — not a generic calorie target. Includes meal plans, supplement protocols, and ongoing macro tuning by clinical nutritionists.
Sleep, stress, circadian rhythm, screen time — the daily inputs most weight programmes ignore. We work with you on sustainable changes that compound over weeks, not crash diets that reverse in months.
Structured to your fitness level, joint health, and metabolic flexibility — resistance training to preserve muscle, zone-2 cardio for fat oxidation, and recovery protocols. No punishment, no extremes.
Stop following generic plans that fail. Start a personalised, root-cause programme led by clinicians who measure progress every step.
“ How root-cause weight management works at Metabalance — from evaluation through long-term reversal. ”
